The Journal of the International Society of Physical and Rehabilitation Medicine

ORIGINAL ARTICLE
Year
: 2022  |  Volume : 5  |  Issue : 3  |  Page : 90--96

A randomized controlled trial to compare the effect of ultrasound-guided, single-dose platelet-rich plasma and corticosteroid injection in patients with carpal tunnel syndrome


Reni Benny1, Srikumar Venkataraman2, Asem Rangita Chanu3, U Singh4, Devasenathipathy Kandasamy5, Raghavendra Lingaiah6 
1 Assistant Professor, Department of Physical Medicine and Rehabilitation, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India
2 Additional Professor, Department of Physical Medicine and Rehabilitation, All India Institute of Medical Sciences, New Delhi, India
3 Associate Professor, Department of Physical Medicine and Rehabilitation, All India Institute of Medical Sciences, New Delhi, India
4 Professor & Head, Department of Physical Medicine and Rehabilitation, Mahatma Gandhi Hospital, MGUMST, Sitapura, Jaipur, Rajasthan, India
5 Professor, Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India
6 Associate Professor, Department of Pathology, SGPGI, Lucknow, India

Correspondence Address:
Dr. Srikumar Venkataraman
All India Institute of Medical Sciences, New Delhi
India

Background: Platelet-rich plasma (PRP) may aid functional recovery in compressive neuropathies. Objective: To compare the effect of autologous PRP with corticosteroid injection in patients with refractory carpal tunnel syndrome (CTS). Materials and Methods: This was a randomized controlled trial on 84 adults, who received either single-dose, ultrasound-guided PRP or corticosteroid. Boston Carpal Tunnel Questionnaire and cross-sectional area of median nerve were assessed at 0, 4, and 12 weeks. Results: A statistically significant 54.76% improvement (P < 0.05) in functional status was observed in both the groups at 12 weeks. Conclusion: PRP is as effective as corticosteroids in relieving pain and improving function in CTS.


How to cite this article:
Benny R, Venkataraman S, Chanu AR, Singh U, Kandasamy D, Lingaiah R. A randomized controlled trial to compare the effect of ultrasound-guided, single-dose platelet-rich plasma and corticosteroid injection in patients with carpal tunnel syndrome.J Int Soc Phys Rehabil Med 2022;5:90-96


How to cite this URL:
Benny R, Venkataraman S, Chanu AR, Singh U, Kandasamy D, Lingaiah R. A randomized controlled trial to compare the effect of ultrasound-guided, single-dose platelet-rich plasma and corticosteroid injection in patients with carpal tunnel syndrome. J Int Soc Phys Rehabil Med [serial online] 2022 [cited 2022 Dec 5 ];5:90-96
Available from: https://www.jisprm.org/article.asp?issn=2349-7904;year=2022;volume=5;issue=3;spage=90;epage=96;aulast=Benny;type=0